Fertility Supplements & Vitamins
Table of Contents
When you’re trying to get pregnant, it’s essential to ensure your body is healthy and is getting all of the key nutrients it needs to develop healthy sperm or eggs. To improve your health and boost your chances of having a baby, our fertility specialists recommend eating a healthy diet and incorporating movement and low-intensity exercises, like yoga, into your daily routine. Unfortunately, many of the nutrients that are vital for reproduction are not always attainable through eating a normal diet alone. Research has shown that fertility supplements can provide the body with crucial nutrients that can boost fertility and improve fertility treatment outcomes.
What are Fertility Supplements?
Fertility supplements are a simple and non-invasive way for you to boost your reproductive health. Fertility supplements are comprised of vitamins, minerals, antioxidants, and other nutrients known to impact fertility. Fertility supplement popularity has increased recently due to people planning to have children later in life, more people being treated for fertility issues, and because they work! The awareness around reproductive health is on the rise, as is the research supporting the role supplements play.
Who should take fertility supplements?
Men and women who are struggling to conceive naturally can and should take fertility supplements. As mentioned above, fertility supplements have been proven effective in supporting couples who are undergoing fertility treatment. Male factor fertility issues are responsible for 33-50% of infertility cases in couples. Men can use fertility supplements to increase the quality of their sperm and their overall health. The other causes of infertility are female infertility, a combination of both male and female fertility issues, and unexplained reasons.
Female fertility supplements can help combat common causes of female infertility like egg quality, diminished ovarian response (DOR), and more. Fertility supplements can even be used to combat one of the leading causes of unexplained fertility, inflammation. Women can also use fertility supplements to support their health throughout and after pregnancy. Supplements can help to improve offspring condition, neurodevelopment, and to protect against metabolic issues.
When should you take fertility supplements?
Sperm and eggs both take about 90 days to develop. For best results, most specialists recommend taking male and female fertility supplements for at least 90 days before trying to conceive naturally or with fertility treatment.
Fertility Supplements for Women
Key Nutrients in Female Fertility Supplements
Choline is an essential nutrient that is vital for many body functions. Choline supports cell growth, metabolism, liver, and muscle function. The body naturally produces choline, but the majority comes from diet.
Doctors and fertility specialists are increasingly recognizing the importance of ensuring adequate levels of choline during pregnancy. Research has shown that choline plays several critical roles in the prenatal period including tissue expansion, brain-development, and neurotransmission . Most pregnant women in the U.S. are not achieving recommended levels of choline. Studies have shown that supplementing mother’s diets with additional choline improves pregnancy outcomes and protects against some neural and metabolic impairments .
Coenzyme Q10 (Co-Q10)
The human body naturally produces Coenzyme Q10 (Co-Q10). Co-Q10 helps generate energy in human cells. An increased amount of Co-Q10 in the blood has been shown to impact both female and male fertility positively. A 2018 study found that pre-supplementation with Co-Q10 improved ovarian response in women undergoing IVF treatment . Co-Q10 has also been shown to improve ovarian reserve, egg quality, and embryo quality.
Female fertility declines rapidly after women turn 40 due to a decrease in oocyte quality and quantity. A 2015 study showed that suboptimal levels of CoQ10 can lead to oocyte deficits and age-associated causes of infertility . The study produced evidence that supplementing Co-Q10 can reverse the age-related decline in oocyte quantity and quality. Simply stated, Co-Q10 helps to combat age-related causes of infertility.
Folate is a type of B-vitamin that is found naturally in food. It is recommended that all women who are trying or planning to get pregnant take a folate supplement to prevent neural birth defects. Trials have shown that women with higher levels of folate had higher live birth rates in comparison to women with lower folate levels . Fertility specialists believe that supplementing folate can improve pregnancy chances for women attempting to get pregnant naturally and for women undergoing fertility treatment. Studies have shown that folate can improve oocyte counts and embryo quality in couples undergoing fertility treatment .
A study of 232 women undergoing fertility treatment showed that higher folate intake was associated with higher rates of implantation, clinical pregnancy, and live birth . Women whose supplemental folate intake was higher experienced higher fertilization rates and lower cycle failure rates prior to embryo transfer.
In a study on healthy women who ovulate regularly, folate supplementation was found to increase progesterone levels and lower the risk for sporadic anovulation . Anovulation occurs when the ovaries do not release an oocyte during a menstrual cycle. Additional studies on how nutrients affect reproduction have shown that folate is essential to oocyte quality and growth, implantation, fetal growth, and organ development .
Inositol is a type of sugar that plays an essential role in many different bodily functions. Inositol is a significant component of cell membranes, it influences insulin production, and it affects chemical messengers in the brain. Poor ovarian response is reported in 9-24% of all IVF cases. Gonadotropin fertility drugs are commonly prescribed to women undergoing fertility treatment to increase ovarian response. Women are considered “poor responders” if their ovaries don’t increase production with gonadtropin fertility drugs. Studies have shown that inositol plays a role in improving ovarian response in women being treated with gonadotropins . Inositol is especially recommended for “low responders” undergoing IVF treatment.
Insulin resistance is a key feature of most women with Polycystic Ovarian Syndrome (PCOS. Inositol has been shown effective to correct insulin resistance in patients with PCOS. A 2016 study showed that supplementing inositol can help treat insulin resistance, lower body mass index, and improve ovarian activity in PCOS patients .
Iodine is a mineral that can be found in seafood or as a dietary supplement. It is an essential element of thyroid hormones and it helps to control cell growth, repair damaged cells, and regulate a healthy metabolism. During early pregnancy, the fetus is dependent on the mother’s thyroid hormones for normal brain development. If thyroid production is affected by low iodine levels than fetal brain development can be affected. Research has shown that taking iodine supplements can help to combat iodine deficiency in pregnant women .
Iodine deficiency is common in the US population, especially pregnant women. Iodine deficiency can also cause women to experience difficulty getting pregnant. In one study, women with low Iodine levels were observed to have a 46% lower chance of achieving pregnancy per menstrual cycle compared to women with sufficient levels .
Iron is an essential mineral for growth, development, and the production of hormones. Iron is used to make hemoglobin, a protein in red blood cells that carries oxygen to organs and tissues throughout the body, and myoglobin, a protein that provides oxygen to muscles. The amount of blood in a woman’s body increases by 30-50% during pregnancy. Extra iron is necessary to support the extra blood volume. Iron deficiency is believed to have an impact on babies being born undersized or prematurely.
Research has also shown that iron levels are related to a woman’s risk of ovulatory infertility. One study showed that women who consumed iron supplements had a significantly lower risk of ovulatory infertility compared to women who did not use iron supplements .
Reservatol is an anti-aging antioxidant and anti-inflammatory compound that can be found in different foods and drinks. Studies have produced evidence that reservatol can help to improve ovarian function in women . Fertility specialists believe that reservatol has therapeutic effects for infertile women suffering from diminished ovarian function, Polycystic Ovarian Syndrome (PCOS), or endometriosis. Studies on women undergoing intracytoplasmic sperm injection (ICSI) have shown that reservatol can improve maturation and oocyte quality .
Vitamin A is vital for normal vision, immune system health, and reproduction. Vitamin A also supports many parts of the body like the heart, lungs, and other organs. Research has shown that Vitamin A is essential for reproduction in both males and females . Studies have shown that supplementing vitamin A can improve egg quality, ovarian response, implantation, embryonic development, and placental function .
Vitamin D helps regulate nutrients that support bone, teeth, and muscle health. A lack of vitamin D can lead to different bone conditions in children and adults. Vitamin D is produced by the body in response to exposure to the sun. It can be difficult for the body to get appropriate levels of Vitamin D through diet and sun exposure alone, especially during the winter months.
Vitamin D provides pregnant women’s bodies with nutrients that support a healthy pregnancy. Vitamin D also helps with calcium absorption. Developing babies receive calcium and vitamin D from the mother during pregnancy; it is important to ensure that both mom and baby have adequate levels of both.
Vitamin D deficiency in mother’s can contribute to the development of childhood rickets and long-term health problems like type 1 diabetes. Vitamin D deficiency is common in pregnant women. Research has shown that most women require vitamin D supplementation to ensure adequate maternal vitamin D levels .
Research has shown that vitamin D supplementation can have a positive impact on pregnancy rates and fertility treatment outcomes. In one study, women with adequate levels of vitamin D had a 52.5% chance of pregnancy per IVF cycle compared to women with insufficient levels only having a 34.7% chance . The women with adequate vitamin D levels also had higher implantation rates.
Omega 3s are known to have a laundry list of health benefits, including lowering blood pressure, reducing the risk of heart attack or stroke, and slowing the development of plaque in arteries. Omega 3s are found naturally in fish, other seafood, some nuts, and seeds. Omega 3 supplements are beneficial for people who don’t regularly consume omega 3 rich seafood as our bodies cannot produce omega 3s. Doctors recommend that everyone, not just people trying to conceive, take an omega 3 supplement.
Women closer to advanced maternal age have lower chances of achieving pregnancy whether they are trying to conceive naturally or with fertility treatments. Studies have shown that increasing omega 3 fatty acid levels can delay ovarian aging and improve oocyte quality in women as they get older . Omega 3s can help reduce age-related causes of infertility.
Studies have shown that omega 3s can improve ovulation, ovarian reserve, and overall fertility . Research has shown that higher omega 3 levels cause an increase in progesterone, a hormone essential to pregnancy that regulates the lining of the uterus. A healthy uterus is essential to the development of a healthy baby.
An Environment and Reproductive Health (EARTH) study displayed that higher levels of omega 3s increase the probability of pregnancy and live birth in women undergoing fertility treatments . Fertility specialists recommend that omega s supplements can be beneficial for all women who are trying to get pregnant.
Best Female Fertility Supplements
We at CNY Fertility have always preached a holistic approach, whether you are trying to conceive naturally or with the help of fertility treatments. In addition to lifestyle and diet changes, we’ve always recommended that both male and female partners take preconception supplements. We are firm believers in the science behind fertility supplements and their effects on improving sperm, egg, embryo, and uterine quality.
Under the direction and guided by the research of Dr. Kiltz and Dr. Mariabelle Verdiales, our fertility specialist in Atlanta (who is also a certified naturopathic doctor), we have formulated what we and other Board Certified Reproductive Endocrinologists believe to be the best fertility supplements available, Molecular Fertility.
Molecular Fertility’s product formulas are backed by peer-reviewed journals and clinical fertility care experience. Board Certified Reproductive Endocrinologists and other fertility experts are already recommending Molecular Fertility products across the USA. Molecular Fertility supplements are packed with all of the essential nutrients listed above. They are independently tested to ensure quality, purity, and potency.
Designed to provide nutritional support to mom and baby pre, during, and post-pregnancy. The nutrients and patented ingredients found in Female Essential + are included to especially prepare moms to be with a strong pre-conception fertile foundation. Female Essential + contains the following ingredients:
- Vitamins A,D, and E
- And many more helpful nutrients!
Specially formulated to give eggs the nutrients they need to develop and bloom. Ovarian Bloom is recommended for females trying to conceive naturally or with the help of fertility treatments. Ovarian Bloom is composed of the following ingredients known to increase female fertility:
- Vitamins D and E
OMEGA Rich Fish Oil is a blend of non-GMO natural fish oils that provides the previously discussed reproductive and general health benefits of omega 3s and vitamins. This product is designed for men and women regardless of their stage of life. Fertility specialists recommend taking this product before trying to conceive, throughout pregnancy and beyond.
Cannabidiol (CBD) is a highly regarded anti-inflammatory. Many fertility experts agree that inflammation is a leading cause of “unexplained” infertility. Molecular Fertiltiy CBD products are designed and tested to ensure they are 100% THC free. In women, CBD can help to restore healthy blood flow and nutrient delivery to the uterus and ovaries by reducing damaging and circulation restricting inflammation.
Male Fertility Supplements
Key Nutrients in Male Fertility Supplements
Coenzyme Q10 (Co-Q10)
Coenzyme Q10 is naturally produced by the human body and helps to generate energy in human cells. Research has shown that CoQ10 supplementation can improve many bodily functions in men including cardiovascular function . Heightened levels of Co-Q10 in the blood have been linked to increased male fertility levels. Recent studies have shown that supplementing Co-Q10 can improve sperm concentration and motility in men, especially those suffering from infertility issues .
CoQ10 supplementation has been found to specifically help infertile men suffering from asthenozoospermia or poor sperm motility . Experts believe this is due to CoQ10s antioxidant properties and its contribution to cell energy production. Another study showed when men with oligoasthenoteratozoospermia, a low number of sperm, were treated with CoQ10 they saw significant increases in sperm concentration and motility .
Acetyl L-Carnitine (ALC)
Acetyl L-Carnitine (ALC) is an antioxidant that is naturally produced by the body. ALC helps the body turn fat into energy. L-Carnitine plays a pivotal role in the maturation of sperm within the male reproductive tract. ALC drives sperm metabolism by providing readily available energy to be used for motility and maturation. Research has shown that supplementing ACL can help to treat male fertility issues, especially those resulting from sperm motility issues .
Additional studies have focused on the effects of l-carnitine supplementation on infertile males . The results showed that treatment with acetyl l-carnitine was effective in improving all sperm parameters, the most significant improvement was in sperm motility. Fertility experts believe that ALC is also important for improving sperm morphology.
Studies have shown that folate plays a vital role in spermatogenesis, the development of sperm cells . Folate is necessary for DNA synthesis, which is an essential process during DNA replication that helps to avoid mutations. Sperm DNA undergoes many more replications compared to oocytes in women. Proper folate levels are necessary to ensure that sperm DNA synthesizes correctly during replication.
Vitamin A has been recognized as a requirement for reproduction since the early 1900s. Research has shown that vitamin A is essential for the maintenance of the male genital tract and spermatogenesis . Vitamin A helps to start cell division in the male gonad. The gonad produces sperm and secretes hormones required for male reproduction. Vitamin A also supports immune health, vision, and has antioxidant properties that support cell growth.
Vitamin D plays an essential role in male reproductive health and general health. Research has shown that vitamin D has a positive effect on male fertility, particularly sperm motility . Other studies show that in addition to supporting sperm motility, vitamin D has a positive effect on overall semen quality .
Studies have shown that around 40% of adults in the U.S. suffer from Vitamin D deficiency. Research has shown vitamin D deficiency can negatively impact infertility in men . A recent study showed that vitamin D deficient men had significantly lower total sperm motility and total number of motile spermatozoa . Fertility specialists recommend supplementing vitamin D to improve the overall health of sperm, including concentration, morphology, and motility.
Another study showed that men suffering from vitamin D deficiency were more likely to have lower testosterone levels . Testosterone is required for many aspects of overall male health including sperm production. Research has shown that supplementing vitamin D can increase testosterone levels by 25% in one year .
Vitamins E and C
Vitamin C is an antioxidant that is known to reduce cellular damage throughout the body. Vitamin C also increases iron absorption. A study of infertile men showed that taking 1,000-mg vitamin C supplements twice a day for up to 2 months increased sperm motility by 92% and sperm count by more than 100% . It also reduced the proportion of deformed sperm cells by 55%. The study displayed that vitamin C supplementation may improve sperm count, sperm motility, and sperm morphology in infertile men.
A review of multiple studies, published in 2016, showed that supplementing vitamins C and E reduces sperm DNA damage and improves sperm count and mobility . Research has shown that supplementing a combination of vitamin C, vitamin E, and CoQ10 can effectively increase semen parameters in infertile men.
Vitamin E is recognized to have positive effects on several different sperm parameters. Recent studies have shown an increase in sperm motility in men who took vitamin E supplements . Research has confirmed the protective and beneficial effects of vitamin E on semen quality. Fertility specialists advocate for the use of vitamin E supplementation for general male infertility treatment and idiopathic male infertility, which is when men have an unexplained reduction of semen quality. Research has shown that supplementing vitamin E can help treat men diagnosed with asthenoteratospermia (abnormal motility and morphology of sperm) or asthenospermia (reduced sperm motility) .
Vitamin B-12 is a nutrient that is involved in the metabolism of every cell in the human body. Vitamin B-12 helps make DNA and also keeps nerve and blood cells healthy. Fertility specialists agree that vitamin B-12 plays an important role in sperm development, as it does with all cells. Research has shown that vitamin B-12 can help improve semen quality, particularly sperm count and sperm motility .
A study conducted in 2013 showed that oral vitamin B-12 supplementation can improve sperm vitality, motility, and DNA integrity . Vitamin B-12 has been proposed by fertility specialists as a candidate therapy to enhance semen quality and also as a candidate drug to manage male infertility because of its positive effects on sperm parameters, particularly sperm count.
Zinc is an essential mineral that is naturally found in meat, fish, and eggs. Getting appropriate levels of Zinc is considered essential for male fertility. Studies show that low zinc levels are associated with low testosterone levels, poor sperm quality, and an increased risk of male infertility . Zinc supplementation has been shown to increase testosterone levels and sperm count in men with low zinc. Men who participate in excessive amounts of high-intensity exercise are more likely to experience low testosterone. Studies have shown that zinc supplementation can especially increase testosterone levels in these men .
Omega 3s have a wide range of health benefits, including that they play a vital role in the structure and formation of all human cells, including sperm. As research continues to develop, there appears to be a link between infertility in men and low omega 3 levels in sperm. Studies have shown that proven fertile men have higher levels of omega 3s compared to infertile men . In addition to supporting the growth of sperm cells, omega 3s can help to boost sperm motility. Another review of studies showed that omega 3 supplementation can improve semen quality parameters in infertile men and men in couples undergoing fertility treatment .
Research has shown that omega 3 supplementation results in enhanced sperm count, sperm motility, and sperm morphology . Fertility specialists believe that men suffering from oligoasthenoteratozoospermia aka OAT (low number of sperm, poor sperm movement, and abnormal sperm shape) may benefit from an omega-3 supplement. OAT is the most common cause of male subfertility.
Best Male Fertility Supplements
Male Essential + was designed to provide men with the nutrients and ingredients that are essential to male fertility and improving men’s overall reproductive health. Male Essential + can be taken by men trying to conceive naturally or with the assistance of fertility treatments. The ingredients included in Male Essential + are:
- Vitamins C, D, E and B12
OMEGA Rich Fish Oil was designed to provide men with the omega 3s and vitamins needed to support cell and sperm development. This blend of omega 3s will support the dietary needs of men throughout every stage of life. Fertility specialists recommend this product to men in all stages of life, especially those trying to conceive naturally and with fertility treatments.
CBD Rich Hemp Oil was designed specifically to combat inflammation. For men, CBD can help restore blood flow and nutrient delivery to the testicles. CBD can also help with sleep, anxiety, and other ailments. As with all of Molecular Fertility’s products, 100% THC free CBD is 3rd party lab-tested to ensure potency and purity.
So what vitamins are essential for fertility? Well, that depends on who’s fertility we are looking to improve. Men’s sperm and women’s eggs require different supportive nutrients. It’s important that men and women take fertility supplements specifically tailored to their biological needs.
Unfortunately, there’s a lot of confusion and misconceptions surrounding fertility supplements, so the need for professional research-backed products is crucial. Our fertility specialists comprising of Board Certified Reproductive Endocrinologists, OBGYNS, and nurse practitioners with special training in fertility wanted to shine a light on the world of fertility supplements and provide you with a brand you can trust for top quality male and female fertility vitamins.