PGD: Screening for Single Gene Diseases


Preimplantation Genetic Diagnosis (PGD) is an incredible tool that we are proud to have available to our clients.  We use PGD in a variety of cases, ranging from clients who are screening for one particular disease, to clients who are hoping to increase their odds of pregnancy by ruling out unknown genetic abnormalities, to those selecting a specific gender.  This video below, recently released by 60 Minutes, highlights some of the many benefits of PGD.

If you would like to discuss your options with PGD, and how it might be beneficial for you, please feel free to schedule an initial consultation if you are a new client, or a follow up talk with one of our providers if you are a current client.  Please fill out this form to begin scheduling your initial consultation, or call our office at any time:  1-800-539-9870


VIDEO: Dr. Robert Kiltz Talks About Single Embryo Transfer


Elective Single Embryo Transfer (ESET) has been a buzz topic lately in the news, amongst reproductive professionals, etc. so Dr. Kiltz recently recorded a video (below) to share his thoughts on the topic and shed some light for our clients and web visitors. If you have any questions about ESET or would like to continue the conversation with us, please bring up the topic at your next consult and we’d be happy to address any and all questions or concerns you may have.
Request Consultation or Appointment
If you are a new patient and would like an initial fertility consultation, in-office or over the phone, please visit this link and fill out our New Appointment Form or call us toll free at 800-539-9870.

DR. ROB KILTZ:  Hi Lisa, how are you?
LISA:  I’m great Dr. Kiltz, how are you doing?
DR. ROB KILTZ:  Spectacular, it’s another wonderful day!
LISA:   Oh, it absolutely is. It’s a great day out and a wonderful day to be taking a look at all of our options here.
DR. ROB KILTZ:   You know it’s interesting, someone said it’s Friday. I looked outside and I couldn’t tell but every day is a good day. What are we going to talk about today?
LISA:   Single embryo transfer. We have a lot of questions about who should maybe look into this option or is it OK to do a single embryo transfer and what are the merits of it?
DR. ROB KILTZ:   Well, single embryo transfer is something we are growing in tremendously. There’s some evidence now that suggests it you put in more than one embryo they may be competing against each other. If the good one implants and the bad one’s kind of starting to implant, it may actually affect the other one. So, I mean, this is somewhat theory but some studies are suggesting this for anecdotal information… certainly I believe for woman under 30, 1 embryo to transfer, 30-35 years of age, 1 or maybe 2 embryos to transfer, and then if you’re older than that, 2 embryos to transfer… that’s the direction we’re moving in.
LISA:  That’s great!
DR. ROB KILTZ:   We’re also looking at offering more and more PGS and PGD, where we biopsy the embryos, identify the normal embryos, and since we’re picking the 1 embryo… we’re more likely to find that 1 embryo. Now since are freezing procedures are doing a lot better, we’re freezing at the blastocyst stage, which is either day 5 or day 6 (sometimes day 7) you can follow them out that way. If you’re not doing PGD or PGS you can still pick that 1 embryo and when you’re thawing that 1, make it 1.
LISA:   That’s great!
DR. ROB KILTZ:   There’s a lot more information that will help to produce multiples and maybe even increase single embryo implantation, obviously a singleton baby.
LISA:   That’s wonderful. I know the idea of, How do you choose? How do you make that decision? is something that weighs heavily on our clients before they have these conversations with our staff but then once they are able to sit down in the office and speak with you or speak with one of our other practitioners… the whole world seems to make a little more sense. We appreciate you taking the time to explain this.
DR. ROB KILTZ:   It is important because it used to be that quite commonly we would implant 4 or 5 embryos, depending on the age and circumstances of the client, but now we are really moving toward doing 1 or 2. We believe that will show some real promise in helping our clients conceive and have babies.
LISA:   Great! Thank you for giving us more information about this and I’m sure you’ll be hearing more from us about other questions we’ll be fielding from clients. And clients if you ever have any questions that you’ll really love for us to address on the clinical side, please don’t hesitate to let us know. We would love to address it, in video format and then of course you can always message us within the Patient Portal and contact us with any questions.
DR. ROB KILTZ:   Always here and thank you, Lisa. God bless!
LISA:   Thank you!


Recent E-Newsletters: Donor Cycles, NIAW and More


For your viewing pleasure we have shared links to a few of our recent e-newsletters below. They are full of helpful information, event invitations, new baby success stories, recent videos and much more. We are always interested in hearing your feedback so if you have any suggestions on how we can better provide you with the information you would like to see, please share your comments here.
If you would like to receive our Fertility E-Newsletters click here.
Holiday Support and National Infertility Awareness Week
Donor Cycles: Determining Blood Type
Laughter for Fertility & PGD Information


The UK welcomes the birth of twins conceived with microarray CGH!


According to ScienceDaily, the UK has joyously welcomed the birth of the first babies conceived with the help of microarray CGH and IVF.  Microarray CGH (or aCGH) is a process that when coupled with IVF, has the potential to greatly increase pregnancy rates.
Much like the couple mentioned in the article, some of our clients experience multiple failed IVF cycles, with no apparent cause.  Sometimes, genetic abnormalities play a role in these cycles.  However, any chromosomal or genetic issues cannot be detected using the typical IVF technology.  A more precise and comprehensive look at each embryo is necessary to rule out any abnormalities.
Utilizing an outside laboratory (Reprogentics) our center is able to sample a tiny portion of a day 3 or day 5 embryo, and assess for genetic abnormalities.  The idea is to then only implant perceivably healthy embryos, and discard any abnormal embryos that may be present.  This will potentially decrease the likelihood of a failed cycle, miscarriage, and/or birth defect.
This is a wonderful addition to our practice, as it gives our practitioners greater precision and offers peace of mind to our clients.  Unfortunately, genetic abnormalities do occur, and account for many pregnancy losses.  However, this great new technology will prevent some of those losses, and generate new hope for many families.
We look forward to offering this technology to more of our clients, and we anxiously await the beautiful births like those welcomed in the UK!  If you would like more information about using microarray CGH with your IVF cycle, please make sure to notify our practitioners early on in your cycle.  There are some factors to consider in the timing of the process, and we want to make sure you have the best chances for an easy and successful cycle.
For more information on Reprogenetics, please feel free to visit their website:
Also, be sure to take a look at Dr. Kiltz’s video about embryo testing and other services provided by Reprogenetics:
We will have many more videos, articles, and testimonials coming your way as we continue to explore this great service!


Comprehensive Fertility Services Offered



Hello, this is Dr. Rob Kiltz of CNY Fertility Center; with locations in Syracuse, Albany, and Rochester, NY.  We see people from all around the world, and are here to help and guide you on this journey, challenging journey, of infertility.  I love to switch the words from infertile to fertile.  Remember, we are what we think, and thoughts create things, and east and west can come together to provide a more integrative fertility treatment approach.  At CNY Fertility and CNY Healing Arts Centers we share both eastern and western practices of medicine.  Science offers much advancement in western medical treatment options and yet, the foundation of spirituality and an eastern practice can be very useful in life.  Studies have shown that support, yoga, acupuncture, and meditation, even prayer, can help with fertility.
Recently, Dr. Stuart Forster had joined us as our full-time male fertility specialist.  Sadly, he passed away.  He did bring great energy and helped us offer a direction that we will continue to move toward as we strive to provide comprehensive fertility for men and women, both evaluation and treatment, as well as support.  Support is so important in our lives each day.  Each day know that all the bumps that come are perfectly there for us to learn, to teach us.  With a positive attitude and persistence, life evolves and we get exactly what we dream and desire… or something better.  Practice each day, be persistent, have the fertility conversation with your friends and family and open up.  Let everyone in your life know what you are experiencing.  It is good, it is healing.  Dr. Herb James and his urology group have been kind enough to offer to continue to assist us in caring for the male fertility portion of our clientele.  We will continue to provide our services and guidance.
Share your story on our blog and connect with others through our Fertile Friends, Support Groups and/or Yoga for Fertility. The Fertile Secret is not a secret; it’s simply a thought, an idea, as you practice good thoughts, good things will come.  When you think the things that happen to you are bad, you will create depression, anxiety, fear, worry, and negative energy.  You feel it in your gut, you feel it in your neck, and the reproductive system feels it too.  Daily meditation can be helpful on your journey to fertility.
Check out our websites:,,  There is a lot of information out there in the world.  Seek it, read it, and know that you are the guide, and we’re here to help in any way that you need.  Please call, ask questions.  Tell us your concerns, and do not hesitate to share your thoughts because we all can do better.
Our mission is to provide the best comprehensive fertility services, western science advances, with our new Micro array and CGH we are now able to test all chromosomes on an embryo. Our partner Reprogenetics assists us in offering everything associated with PGD (preimplantation genetic diagnosis) to our clients at CNY Fertility Center. These services can potentially help to increase outcomes.  We must continue to step back to the simple things of yoga, acupuncture, massage, and meditation.  Thank you for allowing us to help.  If it’s simply a phone call, or an email, we’re there.  Be persistent, always be willing to change it up – I am willing to do that, as we explore and expand, and participate and share.
Blessings and love,
Dr. Rob

Yes, another awesome and amazing day in the Universe.


Over 30 Beautiful babies from Preimplantation Genetic Diagnosis (PGD)!


And we’re still going!  We are proud to have added over 30 lovely babies to the CNY Fertility family, thanks to Preimplantation Genetic Diagnosis, or PGD.
Many of our clients elect to pursue PGD cycles to avoid passing on various genetic diseases to their children.  This offers a great sense of security, and makes for a relaxed and enjoyable pregnancy.  Sometimes, a couple will decide to pursue PGD to balance their family, and select the sex of their next child.  Whatever the reason may be, PGD has expanded and evolved many families, and the numbers are growing.
If you are interested in a PGD cycle, please contact our office for a consultation.  Our practitioners will be happy to walk you through your options, and create the protocol that best fits your needs.
We hope to hear from you, and add another beautiful life to our growing numbers!
To schedule a consultation appointment, please follow this link to our Contact Page.


CNY Fertility Center Video About Embryo Testing, PGD and PGS


Dr. Rob: Hi this is Dr. Rob Kiltz sitting here with Kelly Ketterson from..
Kelly: Reprogenetics..
Dr. Rob: She’s here to help share and help us learn and increase our knowledge about PGD.  What is PGD?
Kelly: Pre-implantation Genetic Screening or Diagnosis, depending on what type of testing you’re doing.
Dr. Rob: It’s all words and it’s important though to understand it and we’re learning and moving to new technology where we typically would do something called “FISH” although it’s still available, you guys offer that also.
Kelly: Right.
Dr. Rob: We’re looking to be able to take a cell from an embryo and…
Kelly: Well, we can either fix it on a slide or put it in a tube and basically we’re looking to analyze the chromosomes in that cell to make sure that the embryo that corresponds to that cell has the right number of chromosomes.
Dr. Rob: So, it allows us to better select embryos that are more likely to create a live-born baby, it can also help identify reasons why someone is not conceiving or maybe miscarrying.
Kelly: Correct.  Often one of the things that patients are worried about is not having an embryo to transfer.  What happens if I don’t have an embryo to transfer?  What I tell patients is that just because you have no normal embryos in a cycle doesn’t always mean that you will never have a normal embryo.  It just means that you’re getting to the point that you’re at where your eggs are less and less likely to produce a normal embryo.  I think it does help patients make some family building options where they can decide if they want to do another cycle and then do the selection process again or think about using a donor egg or moving on to adoption.
Dr. Rob: So this is a good point, because often we do not know when you see beautiful embryos whether it’s an embryo issue or a uterine factor, environment is very critical.  If you had the information that there was a chromosomal abnormality which was more likely the cause of you not conceiving or miscarrying, that would help you to either just continue to be persistent or move onto donor eggs.  If you had normal embryos and they were not implanting, this may lead you to other methods which would improve uterine implantation and/or use a gestational carrier.
Kelly: Correct.  You bring up an important point because FISH limited us; we could only look at so many chromosomes.  We were looking at twelve chromosomes on a routine basis.  New technologies to screen embryos, it’s called Erase CGH and this is a way we can look at all the chromosomes.  There are chromosomes that when there are the wrong number each cell should have two of the chromosomes that we test for, but if there’s one or three, that’s incorrect for the number of chromosomes, but those chromosomes don’t necessarily implant.  Previously, with FISH testing, we were only looking at the chromosomes that would cause a baby to be born with some abnormality, we weren’t’ necessarily looking at chromosomes that would not implant.  Now, we can tell when the embryo is abnormal and will not implant.
Dr. Rob: So this technology has been around for a while and you guys have been providing this technique?
Kelly: We’ve been providing it for about two years now.  Initially, there are many steps in the technique.  You have to take the cell out and instead of fixing it on the slide; you put it into a tube.  When you put it in the tube, there’s not enough DNA in that cell to make a diagnosis, so you have to amplify the DNA, so you have to make many copies of the same cell and that was sort of the initial trick to getting the technique to be consistent on the amplification process.  The first couple of amplification processes that we tried, we didn’t feel like we’re producing consistent results, so we had to optimize that.  So now we feel like for the past year, we’ve really optimized and we look at our diagnosis and we check it again and feel that we are very consistent.
Dr. Rob: Is it to a point where we should be doing this routinely, do you think?
Kelly: We feel that for Day #3 embryos it’s now time to switch from FISH to these methods that will allow us to look at all the chromosomes.
Dr. Rob: I imagine there may be a time where we analyze all embryos for couples to identify these abnormalities and/or looking for the best embryos for implantation.  What’s your thoughts on that?
Kelly: We may get there.  Right now, I think that I would still stay focused on patients with recurrent Miscarriage, repeated IVF failure, patients who have had a previous anueploid conception or conceived a baby with a known abnormality until we can feel that we can show a benefit to the patients that don’t have one of those diagnosis.
Dr. Rob: You’ve had some experience talking to clients because you’ve acted as a coach for many clients going through fertility treatments.  What’s your experience in some of their biggest fears?  You mentioned not getting an embryo to transfer, anything else that comes up?
Kelly: I think that not getting an embryo to transfer is the biggest fear.  There’s no other side effect to the procedure.  The patient doesn’t have to do anything additional to have PGD or there are no additional procedures for them, there are no additional risks to them personally.  The biggest risk is that if a patient has few embryos, you do have to take a cell out and there’s a risk to the embryo when you do that.  You could potentially have an embryo that is diagnosed as normal but then you can’t transfer it because it doesn’t advance.  I think that would be the only other thing that I can think of that would be a concern to the patient.
Dr. Rob: Well, I really appreciate you taking the time to come and visit us and see my fertility center and we talked about doing some monthly seminars, having clients come to our centers and also doing some webinars but you’re also available by telephone for consulting because it really is about connecting and sharing thoughts and ideas and helping people to go through the process and down the journey.  It’s all a journey and thank you, Kelly.
Kelly: Thank you.
Dr. Rob: Reprogenetics…we’ll throw some connections and some numbers that we can also connect.  What’s your website?
Kelly: It’s
Dr. Rob: Don’t forget CNY Fertility,, and  Blessings and enjoy the day, Dr. Rob Kiltz and Kelly.
Kelly: Bye.
Dr. Rob: Have a great day.


Low Cost IVF in the United States


CNY Fertility Center, founded and directed by Dr. Robert J. Kiltz, with offices across New York State, offers low cost fertility/infertility treatment that include IVF, ICSI, PGD, Cryopreservation, Donor Eggs, and much more. Although fertility treatments are offered worldwide, wide variations are noted in different countries in regard to quality and availability. Medical tourism is becoming a popular means for consumers to find state-of-the-art medical care around the globe. We have integrated both Eastern and Western medicine to provide our clients with a holistic approach to their reproductive care. It is our goal at CNY Fertility Center to become the center of choice both across the United States and to our friends abroad.

Our mission is to provide comprehensive reproductive services in a compassionate, honest and friendly environment at a low cost to our clients. In 2010, Dr. Kiltz has created financial plans to minimize the stress on our clients on their journey to build their family. We offer multiple cycle discounts as well as IVF refund programs. Couples interested in donor eggs will also find that we offer exceptional rates in comparison to many other programs and we as well offer both multiple cycle discounts and refund programs for couples/recipients who are interested in pursuing donor eggs.

As our centers grow to offer services across the United States and around the world, we will strive to meet your needs. We understand the inconvenience of leaving your home for medical care and we will assist you in any way we can to make your stay in New York as comfortable and as convenient as possible. We will provide you with continuous support throughout your journey. Our staff is here for you and it would be our pleasure and our honor to help you build your family.

If you are interested in exceptional, quality care, in a warm environment, at a low cost, please visit our website at If you have questions regarding any aspect of the services offered at CNY Fertility Center, please do not hesitate to contact us at (518) 690-0700. Our staff is available 24 hours per day, 7 days a week, to answer any of your questions. We look forward to working with you.

Justine Taylor, RN, BSN
Nurse Manager and IVF Coordinator


Hysterosalpingogram (His-tur-oh-sal-ping-go-gram or HSG)


Although tricky to pronounce, a Hysterosalpingogram (HSG), is a simple in-office procedure that determines whether the fallopian tubes are open, and assesses the presence and condition of fibroids or polyps in the uterine cavity. Very low radiation x-rays are used via fluoroscope, while iodine contrast dye is gently injected into the uterus and fallopian tubes. The procedure takes roughly 20 minutes.
The female patient lies on an exam table under the fluoroscope. A speculum is placed in the vagina, and a catheter is used to administer the contrast dye through the cervical opening into the uterus. Once the dye is injected, the fluoroscope is used to determine whether the dye fills and spills out of the fallopian tubes, indicating the fallopian tubes are open.
An ultrasound called a hysterosonogram, may be performed at the time of the HSG providing an enhanced evaluation of the uterine cavity. A hysterosonogram can provide information that an HSG alone could miss. An HSG is performed for diagnostic purposes; however, there has been some evidence that an HSG may increase fertility in the months following the procedure. There are very few risks associated with this procedure, but it is important to tell your doctor if you are allergic to iodine, IV contrast dyes or seafood. There is an alternative for patients with these allergies.
Patients have rated an HSG as mildly to moderately uncomfortable, experiencing discomfort similar to menstrual cramps. A non-steroidal, such as Advil (Ibuprofen) taken ½ hour prior to the procedure, can minimize this discomfort. After the procedure the patient can resume their normal daily routines. Some spotting may occur, but heavy bleeding should be reported to our staff immediately. CNY Fertility Center offers HSG on-site, alleviating the need to go to a hospital for this procedure. Following the procedure, the doctor will be able to diagnose tubal or uterine factor infertility, and a treatment protocol can be established.


Preimplantation Genetic Diagnosis (PGD)


The latest in IVF technology is now available at CNY Fertility Center!
Preimplantation Genetic Diagnosis (PGD) is a procedure for screening for genetic diseases in an embryo prior to transfer to the uterus. PGD can be used to detect embryos with single gene defects. This allows us to screen for diseases like Tay-Sachs, Cystic Fibrosis, Huntington Disease and Sickle Cell Anemia. PGD can also be used to detect embryos that have chromosomal disorders such as Down’s Syndrome.
PGD must be done in conjunction with IVF. After the eggs are retrieved, they are inseminated with the partner’s sperm via ICSI (Intracytoplasmic Sperm Injection) where they take a single sperm and directly inject it into an egg. If the egg becomes fertilized, it should develop into a 6-10 celled embryo by the third day after fertilization. At this point 1-2 of the embryo’s cells (or blastomeres) are biopsied and then the genetic information is analyzed. The laboratory can then tell which embryos are unaffected for the disease
being screened. Only those unaffected embryos are transferred back to the uterus in hopes of a pregnancy.
For more information on PGD, contact CNY Fertility Center, or visit these websites: